make sure和be sure的区别：含义不同、用法不同、强调重点不同。make sure的含义为“确保”、“务必”、“深信”，是指将某事弄清楚，后面可接of或about引出的短语；be sure的含义为“肯定”、“确定”，是指某人对某事有把握，在句中作表语。

make sure意为确保;务必;尽力做到;深信;务请。

例句：We make sure our clients get the best that money can buy.

我们确保客户买到最好的产品。

Make sure that sign's the right way up.

一定不要把这招牌挂颠倒了。

Make sure you've got a steady hold on the camera.

一定要拿稳相机。

She shook it to make sure there was nothing inside.

她把它晃了晃，以确定里面没有东西。

Make sure you swot up on the company before the interview.

面试前一定要用心掌握公司的情况。

Make sure that your weight is evenly distributed.

注意让你的重量分布均匀。

Make sure you have plenty of room to sit comfortably.

一定要找个宽敞地儿坐得舒服一点。

We try to make sure children don't feel intimidated on their first day at school.

我们努力确保孩子们在上学的第一天不胆怯。

be sure意为确信;肯定;确定。

例句：Before leaving the city, be sure to make time for a shopping trip

离开城市之前，一定要留出时间去买些东西。

Be sure to give your family my regards.

务必代我向你的家人问好。

England must win this game to be sure of qualifying.

英格兰队必须拿下这场比赛才能确保获得资格。

The worst of it is that I can't even be sure if they received my letter.

最糟糕的是，我甚至不能确定他们是否收到了我的信。

Be sure to read about how mozzarella is made, on page 65

务必看看莫泽雷勒干酪是怎么制成的，在第65页。

If you make a threat be sure to carry it out if he errs again.

如果你作出威胁，在他再犯错时，一定要说到做到。