disease和plague的区别：含义不同、词性不同、用法不同。disease作为名词，含义为“疾病”、“弊端”、“痼疾”；plague可作名词和及物动词，含义为“灾害”、“瘟疫”、“困扰”、“给…造成长时间的痛苦”、“缠扰”。

disease作为名词，是可数名词，意为病;疾病;弊端;恶疾;痼疾。

例句：It is not known what causes the disease.

这种病的起因不明。

Greed is a disease of modern society.

贪婪是现代社会的恶疾。

The new drug has great significance for the treatment of the disease.

这种新药对于这种病的治疗有重大的意义。

The test is used to diagnose a variety of diseases.

此项化验可用于诊断多种疾病。

High blood pressure is a common accompaniment to this disease.

这种病通常伴随有高血压。

Extensive research has been done into this disease.

对这种疾病已进行了广泛研究。

Smoking can increase the risk of developing heart disease.

吸烟会增加得心脏病的危险。

plague作为名词和及物动词，意为瘟疫;死亡率高的传染病;困扰;折磨;给…造成长时间的痛苦(或麻烦);使受煎熬;纠缠;缠磨;缠扰。

例句：Financial problems are plaguing the company.

财政问题使这家公司焦头烂额。

Rock stars have to get used to being plagued by autograph hunters.

摇滚歌星必须习惯歌迷要求签名的纠缠。

A cholera plague had been killing many prisoners of war at the time.

当时霍乱疫情已在夺去很多战俘的生命。

The city is under threat from a plague of rats...

该市处于鼠患的威胁之下。

Inflation will remain a recurrent plague...

通货膨胀将继续成为周期性的烦扰。

She was plagued by weakness, fatigue, and dizziness...

她感觉体虚、疲倦、头昏眼花。

I'm not going to plague you with a lot more questions, Miss Culver...

卡尔弗小姐，我不会再问更多的问题来烦你了。